Xavier Coates, Cameron Munster, Harry Grant and Felise Kaufusi have been chosen by Queensland coach Billy Slater for Origin I on Wednesday 8 June.
Returning to the Origin arena, Coates, Munster and Kaufusi have been named in the team's starting line-up with Grant on the interchange.
With all four being a part of the 2020 winning squad, the Maroons will be striving to reclaim the Origin shield the NSW Blues triumphed last year
Maroons Origin I Squad
1. Kalyn Ponga - Newcastle Knights
2. Selwyn Cobbo - Brisbane Broncos
3. Valentine Holmes - North Queensland Cowboys
4. Dane Gagai - Newcastle Knights
5. Xavier Coates - Melbourne Storm
6. Cameron Munster - Melbourne Storm
7. Daly Cherry-Evans - Manly Sea Eagles
8. Tino Fa'asuamaleaui - Gold Coast Titans
9. Ben Hunt - St George Illawarra Dragons
10. Josh Papalii - Canberra Raiders
11. Kurt Capewell - Brisbane Broncos
12. Felise Kaufusi - Melbourne Storm
13. Reuben Cotter - North Queensland Cowboys
14. Harry Grant - Melbourne Storm
15. Lindsay Collins - Sydney Roosters
16. Patrick Carrigan - Brisbane Broncos
17. Jeremiah Nanai - North Queensland Cowboys
18. Tom Dearden - North Queensland Cowboys
19. Jai Arrow - South Sydney Rabbitohs
20. Thomas Flegler - Brisbane Broncos
21. Hamiso Tabuai-Fidow - North Queensland Cowboys
22. Murray Taulagi - North Queensland Cowboys